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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL304591
Molecular formula	C32H36N4O5
IUPAC name	2-(4-methoxyphenyl)-1,3-dioxo-N-[3-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]propyl]isoindole-5-carboxamide
Molecular weight	556.663
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.5
Synonyms	BDBM50088398 N-[3-[4-(2-Isopropoxyphenyl)piperazino]propyl]-2-(4-methoxyphenyl)-1,3-dioxoisoindoline-5-carboxamide 2-(4-Methoxy-phenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid {3-[4-(2-isopropoxy-phenyl)-piperazin-1-yl]-propyl}-amide
Inchi Key	MVYCXEXQTMBCNB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H36N4O5/c1-22(2)41-29-8-5-4-7-28(29)35-19-17-34(18-20-35)16-6-15-33-30(37)23-9-14-26-27(21-23)32(39)36(31(26)38)24-10-12-25(40-3)13-11-24/h4-5,7-14,21-22H,6,15-20H2,1-3H3,(H,33,37)
PubChem CID	10578715
ChEMBL	CHEMBL304591
IUPHAR	N/A
BindingDB	50088398
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
215595	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
215598	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
215597	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
215596	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
215590	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
215592	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
215594	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
215591	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
215588	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
215587	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
215593	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
215589	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488

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