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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	A61603
Molecular formula	C14H19N3O3S
IUPAC name	N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide
Molecular weight	309.384
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	0.4
Synonyms	CHEBI:103854 N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide A-61603 D07OAF NCGC00024968-02 BDBM50118703 Methanesulfonamide,N-[5-(4,5-dihydro-1H-imidazol-2-yl)-5,6,7,8-tetrahydro-2-hydroxy-1-naphthalenyl]-,hydrobromide(1:1) n-[5-(4,5-dihydro-1h-imidazol-2yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulphonamide GTPL480 SCHEMBL8856920 BRD-A83650191-004-01-0 N-[5-(4,5-Dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydro-naphthalen-1-yl]-methanesulfonamide A 61603 CHEMBL109783 N-[[5-[(4,5-Dihydro-1H-imidazol)-2-yl]-2-hydroxy-5,6,7,8-tetrahydronaphthalen]-1-yl]methanesulfonamide AC1N1YI9 L000090 [ Show all ]
Inchi Key	OQFCXJDXHCDLHX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H19N3O3S/c1-21(19,20)17-13-10-3-2-4-11(14-15-7-8-16-14)9(10)5-6-12(13)18/h5-6,11,17-18H,2-4,7-8H2,1H3,(H,15,16)
PubChem CID	4038180
ChEMBL	CHEMBL109783
IUPHAR	480
BindingDB	50118703
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
247708	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
247709	Alpha-1A adrenergic receptor	O02824	ADRA1A	Oryctolagus cuniculus (Rabbit)	466
247713	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
247717	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
247711	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
247714	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
247716	Alpha-1B adrenergic receptor	P18841	ADRA1B	Mesocricetus auratus (Golden hamster)	515
247712	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
247710	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
247715	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453

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