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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL75257
Molecular formula	C16H23N3O
IUPAC name	N-(4-tert-butyl-3-methoxy-2,6-dimethylphenyl)-1H-imidazol-2-amine
Molecular weight	273.38
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	4.3
Synonyms	2-(2,6-Dimethyl-3-methoxy-4-tert-butylanilino)-1H-imidazole (4-tert-Butyl-3-methoxy-2,6-dimethyl-phenyl)-(1H-imidazol-2-yl)-amine BDBM50055835
Inchi Key	AZADEQYOIWOMER-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H23N3O/c1-10-9-12(16(3,4)5)14(20-6)11(2)13(10)19-15-17-7-8-18-15/h7-9H,1-6H3,(H2,17,18,19)
PubChem CID	9795515
ChEMBL	CHEMBL75257
IUPHAR	N/A
BindingDB	50055835
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17944	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
17942	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
17943	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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