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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AGN 192836
Molecular formula	C12H13N3O2
IUPAC name	N-(5-methyl-2,3-dihydro-1,4-benzodioxin-6-yl)-1H-imidazol-2-amine
Molecular weight	231.255
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.0
Synonyms	2-[[(5-Methyl-2,3-dihydro-1,4-benzodioxin)-6-yl]amino]-1H-imidazole HY-100300 AGN192836 (1H-Imidazol-2-yl)-(5-methyl-2,3-dihydro-benzo[1,4]dioxin-6-yl)-amine CHEMBL308570 SCHEMBL7808630 BDBM50055832 171102-29-7 CS-0018452 [ Show all ]
Inchi Key	NDFYRGCPDAFQDG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H13N3O2/c1-8-9(15-12-13-4-5-14-12)2-3-10-11(8)17-7-6-16-10/h2-5H,6-7H2,1H3,(H2,13,14,15)
PubChem CID	10176999
ChEMBL	CHEMBL308570
IUPHAR	N/A
BindingDB	50055832
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
220505	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
220504	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
220503	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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