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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	7-Hydroxychlorpromazine
Molecular formula	C17H19ClN2OS
IUPAC name	8-chloro-10-[3-(dimethylamino)propyl]phenothiazin-3-ol
Molecular weight	334.862
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.8
Synonyms	PHENOTHIAZINE, 2-CHLORO-10-(3-(DIMETHYLAMINO)PROPYL)-7-HYDROXY- 7-Hydroxy Chlorpromazine 8-Chloro-10-[3-(dimethylamino)propyl]-10H-phenothiazin-3-ol CCG-37119 MLS002920079 NSC 131053 UNII-P0X9L6UVP0 CHEMBL909 NCGC00097415-01 NSC_16414 10H-Phenothiazin-3-ol, 8-chloro-10-[3-(dimethylamino)propyl]- 7-OHCPZ BRN 1021503 hydroxychlorpromazine NCIStruc1_001431 Phenothiazin-3-ol, 8-chloro-10-(3-(dimethylamino)propyl)- (8CI) SCHEMBL2389266 7-Hydroxy-2-chloro-10-(3'-(dimethylamino)-N-propyl)phenothiazine 8-Chloro-10-[3-(dimethylamino)propyl]-10H-phenothiazin-3-ol # CHEBI:125475 NCGC00014306 NSC-131053 WLN: T C666 BN ISJ B3N1&1 EG LQ 10H-Phenothiazin-3-ol, 8-chloro-10-(3-(dimethylamino)propyl)- 7-OCPZ AC1L27WF DTXSID20175128 NCI131053 P0X9L6UVP0 Phenothiazin-3-ol, 8-chloro-10-[3-(dimethylamino)propyl]- 2095-62-7 8-Chloro-10-(3-(dimethylamino)propyl)-10H-phenothiazin-3-ol CAS_16414 LS-105368 NCIStruc2_001713 SMR001797676 7-Hydroxy-2-chloro-10-[3'-(dimethylamino)-N-propyl]phenothiazine 8-chloro-10-[3-(dimethylamino)propyl]phenothiazin-3-ol NCGC00014306-02 NSC131053 ZINC1717860 10H-Phenothiazin-3-ol, 8-chloro-10-(3-(dimethylamino)propyl)- (9CI) 7-OH-CHLORPROMAZINE BDBM81812 HICFFJZGXWEIHN-UHFFFAOYSA-N NCI60_000684 Phenothiazin-3-ol, 8-chloro-10-(3-(dimethylamino)propyl)- [ Show all ]
Inchi Key	HICFFJZGXWEIHN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H19ClN2OS/c1-19(2)8-3-9-20-14-6-5-13(21)11-17(14)22-16-7-4-12(18)10-15(16)20/h4-7,10-11,21H,3,8-9H2,1-2H3
PubChem CID	16414
ChEMBL	CHEMBL909
IUPHAR	N/A
BindingDB	81812
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
115541	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
115540	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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