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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Tramazoline
Molecular formula	C13H17N3
IUPAC name	N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine
Molecular weight	215.3
Hydrogen bond acceptor	1
Hydrogen bond donor	2
XlogP	2.0
Synonyms	Imidazolidine,2-[(5,6,7,8-tetrahydronaphthal-1-yl]imino- QQJLHRRUATVHED-UHFFFAOYSA-N Towk Tramazolinum [INN-Latin] 2-(5,6,7,8-tetrahydro-1-naphthylamino)-2-imidazoline 4,5-Dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)-1H-imidazol-2-amine CHEBI:134893 N-(5,6,7,8-Tetrahydro-1-naphthalenyl)-4,5-dihydro-1H-imidazol-2-amine # SCHEMBL121944 Tramazolina [INN-Spanish] 2-imidazolin-2-yl(5,6,7,8-tetrahydro-1-naphthyl)amine AC1Q4UQJ D0ZT8D EINECS 214-105-6 PDSP1_001098 STL483756 Tramazoline [INN:BAN] 1H-Imidazol-2-amine, 4,5-dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)- 2-[(5,6,7,8-tetrahydronaphthalen-1-yl)amino]-2-imidazoline BDBM50027056 L000866 Rhinol TRAMAZOLIN UNII-SLE31693IV 2-(5,6,7,8-tetrahydro-1-naphthylimino)-imidazolidine CHEMBL32573 DB13064 N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine SCHEMBL8623881 082T571 2-imidazolin-2-yl(5,6,7,8-tetrahydro-1-naphthyl)amine tramazoline 2-(5,6,7,8-Tetrahydro-1-naphthylamino)-2-imidazoline 4,5-Dihydro- AN-48480 Imidazolidin-2-ylidene-(5,6,7,8-tetrahydro-naphthalen-1-yl)-amine PDSP2_001082 Tobispray Tramazolinum 2-(5,6,7, 8-tetrahydro-1-naphthylimino)-imidazolidine 3715-90-0 (mono-hydrochloride) BDBM50225288 Muconasal (TN) Rhynaspray Tramazolina ZINC1534528 (4,5-Dihydro-1H-imidazol-2-yl)-(5,6,7,8-tetrahydro-naphthalen-1-yl)-amine 2-(5,6,7,8-tetrahydronaphthalen-1-ylamino)-2-imidazoline AC1L1KJB D08624 DTXSID5046936 N-tetralin-5-yl-4,5-dihydro-1H-imidazol-2-amine SLE31693IV Tramazoline (INN) 1082-57-1 2-[(5,6,7,8-Tetrahydro-1-naphthyl)amino]-2-imidazoline BCP29020 [ Show all ]
Inchi Key	QQJLHRRUATVHED-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H17N3/c1-2-6-11-10(4-1)5-3-7-12(11)16-13-14-8-9-15-13/h3,5,7H,1-2,4,6,8-9H2,(H2,14,15,16)
PubChem CID	5524
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50027056
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
556579	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
556580	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
284410	Alpha-2A adrenergic receptor	Q01338	Adra2a	Mus musculus (Mouse)	450
284411	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
284409	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
284408	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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