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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	LP-211
Molecular formula	C30H34N4O
IUPAC name	N-[(4-cyanophenyl)methyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Molecular weight	466.629
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.0
Synonyms	1052147-86-0 CS-0040944 LP-211; LP 211; LP2111052147-86-0 N-[(4-cyanophenyl)methyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide AKOS016340412 HG-0230 CHEMBL522691 D00GSD MolPort-035-395-277 ZINC40424136 BDBM50253281 HY-111455 compound 25 [PMID 18800769] LP-211, >=98% (HPLC) GTPL8436 N-(4-Cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide KS-00002WTQ [ Show all ]
Inchi Key	BQEDZLDNNBDKDS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H34N4O/c31-23-25-14-16-26(17-15-25)24-32-30(35)13-5-2-8-18-33-19-21-34(22-20-33)29-12-7-6-11-28(29)27-9-3-1-4-10-27/h1,3-4,6-7,9-12,14-17H,2,5,8,13,18-22,24H2,(H,32,35)
PubChem CID	25107716
ChEMBL	CHEMBL522691
IUPHAR	8436
BindingDB	50253281
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
30220	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
536749	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
30216	5-hydroxytryptamine receptor 7	P50407	HTR7	Cavia porcellus (Guinea pig)	446
30218	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
30219	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
536748	5-hydroxytryptamine receptor 7	P32304	Htr7	Mus musculus (Mouse)	448
30217	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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