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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL109360
Molecular formula	C17H24N2O2
IUPAC name	[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl] 2,2-dimethylpropanoate
Molecular weight	288.391
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.7
Synonyms	2,2-Dimethyl-propionic acid 3-(2-dimethylamino-ethyl)-1H-indol-5-yl ester BDBM50049073 ZINC13745609 2,2-Dimethylpropionic acid 3-[2-(dimethylamino)ethyl]-1H-indol-5-yl ester
Inchi Key	AFACMZRKVDGTKP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H24N2O2/c1-17(2,3)16(20)21-13-6-7-15-14(10-13)12(11-18-15)8-9-19(4)5/h6-7,10-11,18H,8-9H2,1-5H3
PubChem CID	44339071
ChEMBL	CHEMBL109360
IUPHAR	N/A
BindingDB	50049073
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3986	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
3985	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377

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