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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL309872
Molecular formula	C25H26ClN3O2
IUPAC name	1-[2-[4-(6-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3,4-dihydro-1H-isochromene-6-carboxamide
Molecular weight	435.952
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.5
Synonyms	1-{2-[4-(6-Chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide BDBM50145342
Inchi Key	BGSCMPXCMQXFNP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H26ClN3O2/c26-19-2-4-21-22(15-28-23(21)14-19)16-5-9-29(10-6-16)11-7-24-20-3-1-18(25(27)30)13-17(20)8-12-31-24/h1-5,13-15,24,28H,6-12H2,(H2,27,30)
PubChem CID	44461266
ChEMBL	CHEMBL309872
IUPHAR	N/A
BindingDB	50145342
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23382	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
23381	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377

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