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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL162771
Molecular formula	C26H36N4O
IUPAC name	N-[4-[3-(2-pyrrolidin-1-ylethyl)-1H-indol-5-yl]-3,6-dihydro-2H-pyridin-1-yl]cyclohexanecarboxamide
Molecular weight	420.601
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	4.6
Synonyms	BDBM50139521 Cyclohexanecarboxylic acid {4-[3-(2-pyrrolidin-1-yl-ethyl)-1H-indol-5-yl]-3,6-dihydro-2H-pyridin-1-yl}-amide
Inchi Key	BARRGRIMEJNOGZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H36N4O/c31-26(21-6-2-1-3-7-21)28-30-16-11-20(12-17-30)22-8-9-25-24(18-22)23(19-27-25)10-15-29-13-4-5-14-29/h8-9,11,18-19,21,27H,1-7,10,12-17H2,(H,28,31)
PubChem CID	44376494
ChEMBL	CHEMBL162771
IUPHAR	N/A
BindingDB	50139521
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
19114	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
19113	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377

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