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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL198488
Molecular formula	C31H33N7O
IUPAC name	4-[5-ethyl-4-[8-(4-propan-2-ylpiperazin-1-yl)-2,3-dihydropyrrolo[3,2-g]isoquinoline-1-carbonyl]pyrazol-1-yl]benzonitrile
Molecular weight	519.653
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.7
Synonyms	BDBM50410425
Inchi Key	AMELELHWAJMSSS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H33N7O/c1-4-28-27(20-34-38(28)25-7-5-22(19-32)6-8-25)31(39)37-12-10-24-17-23-9-11-33-30(26(23)18-29(24)37)36-15-13-35(14-16-36)21(2)3/h5-9,11,17-18,20-21H,4,10,12-16H2,1-3H3
PubChem CID	44404260
ChEMBL	CHEMBL198488
IUPHAR	N/A
BindingDB	50410425
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8804	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
8803	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
8805	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377

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