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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL511279
Molecular formula	C26H28F2N4O2
IUPAC name	4-(2,2-difluoroethyl)-8-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Molecular weight	466.533
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	4.5
Synonyms	BDBM50413557
Inchi Key	BILQJDKHRSUCQZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H28F2N4O2/c1-18-8-9-20-21(29-18)5-3-6-22(20)31-14-12-30(13-15-31)11-10-19-4-2-7-23-26(19)34-17-25(33)32(23)16-24(27)28/h2-9,24H,10-17H2,1H3
PubChem CID	44592252
ChEMBL	CHEMBL511279
IUPHAR	N/A
BindingDB	50413557
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
24534	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
24536	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
24535	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377

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