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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL79725
Molecular formula	C24H26FN3O2
IUPAC name	1-[2-[3-(6-fluoro-1H-indol-3-yl)pyrrolidin-1-yl]ethyl]-3,4-dihydro-1H-isochromene-6-carboxamide
Molecular weight	407.489
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.0
Synonyms	1-{2-[3-(6-Fluoro-1H-indol-3-yl)-pyrrolidin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide BDBM50145352
Inchi Key	ASDKFOKSFQKONG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H26FN3O2/c25-18-2-4-20-21(13-27-22(20)12-18)17-5-8-28(14-17)9-6-23-19-3-1-16(24(26)29)11-15(19)7-10-30-23/h1-4,11-13,17,23,27H,5-10,14H2,(H2,26,29)
PubChem CID	44461248
ChEMBL	CHEMBL79725
IUPHAR	N/A
BindingDB	50145352
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
13028	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
13026	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
13027	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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