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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL357034
Molecular formula	C15H22N2
IUPAC name	2-(5-tert-butyl-1H-indol-3-yl)-N-methylethanamine
Molecular weight	230.355
Hydrogen bond acceptor	1
Hydrogen bond donor	2
XlogP	3.2
Synonyms	ZINC2005821 AKOS022799875 5-tert-Butyl-3-[2-(methylamino)ethyl]-1H-indole [2-(5-tert-Butyl-1H-indol-3-yl)-ethyl]-methyl-amine BDBM50073688 SCHEMBL19971718 [ Show all ]
Inchi Key	BEPGJIBRVXQULF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H22N2/c1-15(2,3)12-5-6-14-13(9-12)11(10-17-14)7-8-16-4/h5-6,9-10,16-17H,7-8H2,1-4H3
PubChem CID	10376578
ChEMBL	CHEMBL357034
IUPHAR	N/A
BindingDB	50073688
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21785	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
21787	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
21786	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377

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