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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2159463
Molecular formula	C22H27FN2O3
IUPAC name	2-ethoxy-N-[1-[2-(3-fluorophenoxy)ethyl]piperidin-4-yl]benzamide
Molecular weight	386.467
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.9
Synonyms	BDBM50393369
Inchi Key	AMFHRDQSGJPBOQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H27FN2O3/c1-2-27-21-9-4-3-8-20(21)22(26)24-18-10-12-25(13-11-18)14-15-28-19-7-5-6-17(23)16-19/h3-9,16,18H,2,10-15H2,1H3,(H,24,26)
PubChem CID	71451456
ChEMBL	CHEMBL2159463
IUPHAR	N/A
BindingDB	50393369
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8828	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
8827	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
8829	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
8830	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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