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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3818805
Molecular formula	C24H27ClN4O
IUPAC name	6-chloro-3-[1-[4-(1H-indol-3-yl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one
Molecular weight	422.957
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	4.8
Synonyms	BDBM50183073
Inchi Key	ADUYXHYSTCIMEO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H27ClN4O/c25-18-8-9-23-22(15-18)27-24(30)29(23)19-10-13-28(14-11-19)12-4-3-5-17-16-26-21-7-2-1-6-20(17)21/h1-2,6-9,15-16,19,26H,3-5,10-14H2,(H,27,30)
PubChem CID	127052487
ChEMBL	CHEMBL3818805
IUPHAR	N/A
BindingDB	50183073
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
521532	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
521529	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
521531	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
521536	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
521534	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
521530	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
521537	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
521535	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
521533	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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