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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2159481
Molecular formula	C24H24F2N2O3S
IUPAC name	3,4-difluoro-N-[1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Molecular weight	458.524
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.6
Synonyms	BDBM50393387
Inchi Key	AJRQMVCEFKRUBB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H24F2N2O3S/c25-22-11-10-20(16-23(22)26)32(29,30)27-19-12-13-28(17-19)14-15-31-24-9-5-4-8-21(24)18-6-2-1-3-7-18/h1-11,16,19,27H,12-15,17H2
PubChem CID	71449643
ChEMBL	CHEMBL2159481
IUPHAR	N/A
BindingDB	50393387
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7175	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
7176	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
7173	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
7174	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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