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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2159474
Molecular formula	C16H17Cl3N2O3S2
IUPAC name	5-chloro-N-[1-[2-(2,3-dichlorophenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Molecular weight	455.793
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.0
Synonyms	BDBM50393380
Inchi Key	AFYGMVTVTLNALM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H17Cl3N2O3S2/c17-12-2-1-3-13(16(12)19)24-9-8-21-7-6-11(10-21)20-26(22,23)15-5-4-14(18)25-15/h1-5,11,20H,6-10H2
PubChem CID	71458650
ChEMBL	CHEMBL2159474
IUPHAR	N/A
BindingDB	50393380
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4610	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
4611	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
4613	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
4612	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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