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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL495250
Molecular formula	C22H28F3N3O3S
IUPAC name	4-methoxy-N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butan-2-yl]benzenesulfonamide
Molecular weight	471.539
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	4.2
Synonyms	BDBM50260644 4-Methoxy-N-{3-[4-(m-trifluoromethylphenyl)-piperazin-1-yl]-1-methyl-propyl}-benzenesulfonamide
Inchi Key	ARWQQHFFCBOLCO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28F3N3O3S/c1-17(26-32(29,30)21-8-6-20(31-2)7-9-21)10-11-27-12-14-28(15-13-27)19-5-3-4-18(16-19)22(23,24)25/h3-9,16-17,26H,10-15H2,1-2H3
PubChem CID	42635388
ChEMBL	CHEMBL495250
IUPHAR	N/A
BindingDB	50260644
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12843	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
12840	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
12844	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
12841	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
12842	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479

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