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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3883388
Molecular formula	C27H27Cl2FN4O3
IUPAC name	2-(3,4-dichlorophenyl)-6-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy]-4,5-dimethylpyridazin-3-one
Molecular weight	545.436
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	6.0
Synonyms	BDBM50208440
Inchi Key	AATQZRYKNHNEDJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H27Cl2FN4O3/c1-16-17(2)27(35)34(20-5-7-22(28)23(29)15-20)31-26(16)36-13-3-10-33-11-8-18(9-12-33)25-21-6-4-19(30)14-24(21)37-32-25/h4-7,14-15,18H,3,8-13H2,1-2H3
PubChem CID	134131479
ChEMBL	CHEMBL3883388
IUPHAR	N/A
BindingDB	50208440
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
547905	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
547904	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
547906	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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