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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL566890
Molecular formula	C22H26ClN7O2
IUPAC name	6-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-2,4-dimethylpurino[7,8-a]imidazole-1,3-dione
Molecular weight	455.947
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.0
Synonyms	8-[3-(N4-3''-chlorophenyl)-piperazin-N1-yl-propyl]-1,3-dimethyl-(1H,8H)-imidazo[2,1-f]purine-2,4-dione BDBM50301631
Inchi Key	AEQRKKLCVSMSAY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H26ClN7O2/c1-25-19-18(20(31)26(2)22(25)32)30-14-13-29(21(30)24-19)8-4-7-27-9-11-28(12-10-27)17-6-3-5-16(23)15-17/h3,5-6,13-15H,4,7-12H2,1-2H3
PubChem CID	44512622
ChEMBL	CHEMBL566890
IUPHAR	N/A
BindingDB	50301631
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3765	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
3764	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
3763	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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