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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3883495
Molecular formula	C23H23Cl2FN4O2
IUPAC name	2-(3,4-dichlorophenyl)-6-[3-[4-(4-fluorophenyl)piperazin-1-yl]propoxy]pyridazin-3-one
Molecular weight	477.361
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.8
Synonyms	BDBM50208483
Inchi Key	ANAAEVFNRAOJLN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H23Cl2FN4O2/c24-20-7-6-19(16-21(20)25)30-23(31)9-8-22(27-30)32-15-1-10-28-11-13-29(14-12-28)18-4-2-17(26)3-5-18/h2-9,16H,1,10-15H2
PubChem CID	134131278
ChEMBL	CHEMBL3883495
IUPHAR	N/A
BindingDB	50208483
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
547989	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
547990	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
547988	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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