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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1783352
Molecular formula	C24H26N6
IUPAC name	N-cyano-N'-[3-(4-naphthalen-1-ylpiperazin-1-yl)propyl]pyridine-4-carboximidamide
Molecular weight	398.514
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.5
Synonyms	BDBM50346381 N''-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)isonicotinamidine
Inchi Key	AAKZKXONERDTDD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H26N6/c25-19-28-24(21-9-12-26-13-10-21)27-11-4-14-29-15-17-30(18-16-29)23-8-3-6-20-5-1-2-7-22(20)23/h1-3,5-10,12-13H,4,11,14-18H2,(H,27,28)
PubChem CID	53304674
ChEMBL	CHEMBL1783352
IUPHAR	N/A
BindingDB	50346381
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
292	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
290	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
291	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
293	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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