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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL476260
Molecular formula	C23H25ClN4O3
IUPAC name	N-[(3S)-1-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]-2,5-dioxopyrrolidin-3-yl]benzamide
Molecular weight	440.928
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.5
Synonyms	(S)-N-(1-(2-(4-(3-chlorophenyl)piperazin-1-yl)ethyl)-2,5-dioxopyrrolidin-3-yl)benzamide BDBM50267229
Inchi Key	AQUXMLXSEGAQLH-FQEVSTJZSA-N
Inchi ID	InChI=1S/C23H25ClN4O3/c24-18-7-4-8-19(15-18)27-12-9-26(10-13-27)11-14-28-21(29)16-20(23(28)31)25-22(30)17-5-2-1-3-6-17/h1-8,15,20H,9-14,16H2,(H,25,30)/t20-/m0/s1
PubChem CID	25270998
ChEMBL	CHEMBL476260
IUPHAR	N/A
BindingDB	50267229
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12124	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
12125	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471

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