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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	60547-97-9
Molecular formula	C14H19N5O2
IUPAC name	6,7-dimethoxy-2-piperazin-1-ylquinazolin-4-amine
Molecular weight	289.339
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	1.0
Synonyms	CP-244 MCULE-2215314767 SC-46103 2-(1-piperazinyl)-4-amino-6,7-dimethoxy-quinazoline UNII-1X8JI3451K 2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline 4-Amino-6,7-dimethoxy-2-piperazino-quinazoline 6,7-dimethoxy-2-piperazin-1-ylquinazolin-4-amine AJ-17877 BC211845 EU-0016066 Oprea1_697372 SMR000069167 2-Piperazine-4-Amino-6,7-Dimethoxy Quinazoline ZX-AT020488 4-amino-6,7-dimethoxy-2-(1-piperazinyl) quinazoline 4-amino-6,7-dimethyoxy-2-(1-piperazinyl)quinazoline 6,7-Dimethoxy-2-(1-piperazinyl)-4-quinazolinamine # 6,7-dimethoxy-2-piperazinylquinazoline-4-ylamine AMINODIMETHOXYQUINAZOLINYLPIPERAZINE (PIPERAZINE DERIVATIVE OF TERAZOSIN) CBDivE_007723 KS-1023 QUI029 0EC TC-159460 2-Piperazino-6,7-dimethoxyquinazoline-4-amine 4-Amino-6,7-dimethoxy-2-(1-piperazinyl)quinqzoline 4-Quinazolinamine, 6,7-dimethoxy-2-(1-piperazinyl)- 6,7-dimethoxy-2-piperazin-1-yl-quinazolin-4-amine AC1LDCWJ APKHJGDGWQDBGM-UHFFFAOYSA-N CHEMBL1226 CTK5B1671 MLS000060939 SCHEMBL608966 2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline VU0000318-6 4-amino-2-(1-piperazinyl)-6,7-dimethoxyquinazoline 4-amino-6,7-dimethoxy-2-piperazinoquinazoline 547D979 6,7-Dimethoxy-2-piperazino-4-aminoquinazoline AK105265 BDBM50073568 FT-0640697 OR14899 ST088140 2-piperazine-4-amino-6,7-dimethoxyquinazoline 4-amino-6,7-dimethoxy-2-(1-piperazinyl)-quinazoline 4-amino-6,7dimethoxy-2-(1-piperazinyl)quinazoline 6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine AN-39430 CC-22341 cid_616267 M-1331 REGID_for_CID_616267 1X8JI3451K TL8003833 2-piperazinyl-4-amino-6,7-dimethoxy quinazoline 4-amino-6,7-dimethoxy-2-(1-piperzinyl)quinazoline 4-Quinazolinamine,6,7-dimethoxy-2-(1-piperazinyl)- 6,7-Dimethoxy-2-piperazin-1-yl-quinazolin-4-ylamine AC1Q4EXP AX8005463 DTXSID00209293 MolPort-001-840-027 SDCCGMLS-0023979.P002 2-Padqz ZINC203311 4-amino-2-piperazin-1-yl-6,7-dimethoxy-quinazoline 4-amino-6,7-dimethyoxy-2-(1-piperazinyl)-quinazoline 6,7-Dimethoxy-2-(1-piperazinyl)-4-quinazolinamine 6,7-Dimethoxy-2-piperazino-4-quinazolinylamine AKOS005713694 C-18181 HMS2421B15 PubChem9673 STL084882 2-piperazino-4-amino-6,7-dimethoxyquinazoline 4-amino-6,7-dimethoxy-2-(1-piperazinyl)quinazoline 4-Quinazolinamine, 6,7-dimethoxy-2-(1-piperazinyl) 6,7-Dimethoxy-2-piperazin-1-yl-quinazolin- AC-17537 ANW-70715 [ Show all ]
Inchi Key	APKHJGDGWQDBGM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H19N5O2/c1-20-11-7-9-10(8-12(11)21-2)17-14(18-13(9)15)19-5-3-16-4-6-19/h7-8,16H,3-6H2,1-2H3,(H2,15,17,18)
PubChem CID	616267
ChEMBL	CHEMBL1226
IUPHAR	N/A
BindingDB	50073568
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11084	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
11081	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
11082	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
11083	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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