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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL317333
Molecular formula	C26H24FN5
IUPAC name	3-[4-[1-(4-fluorophenyl)-5-pyrimidin-2-ylindol-3-yl]piperidin-1-yl]propanenitrile
Molecular weight	425.511
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.0
Synonyms	BDBM50122806 SCHEMBL6598143 3-{4-[1-(4-Fluoro-phenyl)-5-pyrimidin-2-yl-1H-indol-3-yl]-piperidin-1-yl}-propionitrile
Inchi Key	ALBWWALSEOWKRA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H24FN5/c27-21-4-6-22(7-5-21)32-18-24(19-9-15-31(16-10-19)14-1-11-28)23-17-20(3-8-25(23)32)26-29-12-2-13-30-26/h2-8,12-13,17-19H,1,9-10,14-16H2
PubChem CID	10310103
ChEMBL	CHEMBL317333
IUPHAR	N/A
BindingDB	50122806
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
8116	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
8120	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
8115	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
8112	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
8118	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
8113	Alpha-1B adrenergic receptor	P18841	ADRA1B	Mesocricetus auratus (Golden hamster)	515
8117	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
8119	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
8111	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
8110	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
8114	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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