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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL122047
Molecular formula	C25H30ClFN4O2
IUPAC name	1-[2-[2-[6-chloro-1-(4-fluorophenyl)indol-3-yl]oxyethyl-methylamino]ethyl]-3-propan-2-ylimidazolidin-2-one
Molecular weight	472.989
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.5
Synonyms	1-[2-({2-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yloxy]-ethyl}-methyl-amino)-ethyl]-3-isopropyl-imidazolidin-2-one BDBM50053206 SCHEMBL8112813
Inchi Key	AAJVCKWMBZMPTO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H30ClFN4O2/c1-18(2)30-13-12-29(25(30)32)11-10-28(3)14-15-33-24-17-31(21-7-5-20(27)6-8-21)23-16-19(26)4-9-22(23)24/h4-9,16-18H,10-15H2,1-3H3
PubChem CID	10528455
ChEMBL	CHEMBL122047
IUPHAR	N/A
BindingDB	50053206
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
260	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
261	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
262	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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