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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL21150
Molecular formula	C26H26ClN3OS
IUPAC name	(3E)-1-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-3-(thiophen-2-ylmethylidene)indol-2-one
Molecular weight	464.024
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.4
Synonyms	1-[3-[4-(3-Chlorophenyl)piperazino]propyl]-3-[(E)-(2-thienyl)methylene]indoline-2-one BDBM50099502 1-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-3-[1-thiophen-2-yl-meth-(E)-ylidene]-1,3-dihydro-indol-2-one
Inchi Key	AFHGICYMZHHOKC-LYBHJNIJSA-N
Inchi ID	InChI=1S/C26H26ClN3OS/c27-20-6-3-7-21(18-20)29-15-13-28(14-16-29)11-5-12-30-25-10-2-1-9-23(25)24(26(30)31)19-22-8-4-17-32-22/h1-4,6-10,17-19H,5,11-16H2/b24-19+
PubChem CID	44273919
ChEMBL	CHEMBL21150
IUPHAR	N/A
BindingDB	50099502
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4154	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
4155	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471

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