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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1076586
Molecular formula	C26H23N3O2
IUPAC name	[4-(1H-indole-6-carbonyl)piperazin-1-yl]-(4-phenylphenyl)methanone
Molecular weight	409.489
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.1
Synonyms	HMS522F18 piperazine,1-([1,1'-biphenyl]-4-ylcarbonyl)-4-(1h-indol-6-ylcarbonyl)- [4-(1H-indole-6-carbonyl)piperazin-1-yl]-(4-phenylphenyl)methanone (4-(1H-indole-6-carbonyl)piperazin-1-yl)(biphenyl-4-yl)methanone KB-275017 AC1MV1XZ SCHEMBL14028477 351858-51-0 Peakdale1_001536 BDBM50312770 ZINC1501732 [ Show all ]
Inchi Key	APHXKHUFVKITGC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H23N3O2/c30-25(22-9-6-20(7-10-22)19-4-2-1-3-5-19)28-14-16-29(17-15-28)26(31)23-11-8-21-12-13-27-24(21)18-23/h1-13,18,27H,14-17H2
PubChem CID	3676358
ChEMBL	CHEMBL1076586
IUPHAR	N/A
BindingDB	50312770
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10988	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
10990	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
10985	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
10986	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
10994	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
10989	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366
10991	Growth hormone secretagogue receptor type 1	O08725	Ghsr	Rattus norvegicus (Rat)	364
10995	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
10993	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
10987	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
10992	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590

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