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| Name | Growth hormone secretagogue receptor type 1 |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Ghsr |
| Synonym | GH-releasing peptide receptor Ghrelin receptor ghrelin receptor 1a GHRP GHS-R [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 364 |
| Amino acid sequence | MWNATPSEEPEPNVTLDLDWDASPGNDSLPDELLPLFPAPLLAGVTATCVALFVVGISGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHENGTDPRDTNECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKSSINT |
| UniProt | O08725 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3278 |
| IUPHAR | 246 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 7647 |  CHEMBL1081612 | C28H26FN3O2 | 455.533 | 3 / 1 | 5.0 | Yes |
| 8763 |  CHEMBL13383 | C28H32N4O3 | 472.589 | 4 / 3 | 2.7 | Yes |
| 10991 |  CHEMBL1076586 | C26H23N3O2 | 409.489 | 2 / 1 | 4.1 | Yes |
| 14909 |  CHEMBL1079622 | C26H23ClN4O2 | 458.946 | 3 / 1 | 4.4 | Yes |
| 17288 |  L-692,585 | C32H37N7O3 | 567.694 | 7 / 4 | 3.8 | No |
| 17290 |  CHEMBL274665 | C32H37N7O3 | 567.694 | 7 / 4 | 3.8 | No |
| 18644 |  CHEMBL441345 | C33H39N7O2 | 565.722 | 6 / 3 | 5.4 | No |
| 465770 |  CHEMBL3593814 | C29H29ClN4O5 | 549.024 | 7 / 3 | 4.5 | No |
| 465940 |  CHEMBL3586030 | C29H30N4O6 | 530.581 | 9 / 2 | 4.2 | No |
| 466396 |  CHEMBL3593633 | C33H36N4O4 | 552.675 | 6 / 2 | 4.6 | No |
| 29087 |  CHEMBL427806 | C28H34N4O2 | 458.606 | 3 / 3 | 3.5 | Yes |
| 30085 |  CHEMBL434609 | C32H38F2N4O3 | 564.678 | 6 / 2 | 4.4 | No |
| 36043 |  CHEMBL392077 | C25H31N7O4S | 525.628 | 8 / 2 | 1.5 | No |
| 467742 |  CHEMBL3593635 | C33H35ClN4O4 | 587.117 | 6 / 2 | 5.1 | No |
| 54678 |  CHEMBL1080735 | C28H24F3N3O2 | 491.514 | 5 / 1 | 5.4 | No |
| 57797 |  CHEMBL1079624 | C26H24N4O2 | 424.504 | 3 / 1 | 3.4 | Yes |
| 61597 |  CHEMBL274237 | C31H35N7O3 | 553.667 | 7 / 4 | 3.4 | No |
| 70954 |  CHEMBL431668 | C34H44N4O4 | 572.75 | 5 / 3 | 4.0 | No |
| 72685 |  CHEMBL14247 | C30H33N7O2 | 523.641 | 6 / 3 | 3.4 | No |
| 77562 |  CHEMBL122939 | C34H46N4O4S | 606.826 | 6 / 3 | 3.7 | No |
| 85120 |  CHEMBL121960 | C30H38N4O3S | 534.719 | 5 / 2 | 4.0 | No |
| 90366 |  CHEMBL269447 | C28H34N4O2 | 458.606 | 3 / 3 | 3.5 | Yes |
| 474463 |  CHEMBL3593636 | C32H33ClN4O5 | 589.089 | 7 / 2 | 4.9 | No |
| 96053 |  CHEMBL1082211 | C27H25N3O2 | 423.516 | 2 / 1 | 4.5 | Yes |
| 98520 |  CHEMBL13930 | C28H34N4O3 | 474.605 | 4 / 3 | 3.3 | Yes |
| 107177 |  CHEMBL1088038 | C26H23FN4O2 | 442.494 | 4 / 1 | 3.5 | Yes |
| 111975 |  CHEMBL1081301 | C26H24N4O2 | 424.504 | 3 / 1 | 3.5 | Yes |
| 112073 |  CHEMBL268518 | C28H34N4O2 | 458.606 | 3 / 3 | 3.3 | Yes |
| 476846 |  CHEMBL3586031 | C30H30N4O6 | 542.592 | 8 / 2 | 3.5 | No |
| 117822 |  CHEMBL238155 | C23H28N6O2 | 420.517 | 6 / 2 | 2.0 | Yes |
| 118148 |  CHEMBL274786 | C26H25N7O2 | 467.533 | 6 / 3 | 2.5 | Yes |
| 553893 |  Pralmorelin | C45H55N9O6 | 817.992 | 8 / 9 | 2.5 | No |
| 129209 |  CHEMBL416712 | C29H31N7O2 | 509.614 | 6 / 3 | 3.9 | No |
| 132355 |  CHEMBL122420 | C32H40N4O3 | 528.697 | 4 / 2 | 4.2 | No |
| 162498 |  CHEMBL13984 | C28H29N7O2 | 495.587 | 6 / 3 | 3.1 | Yes |
| 483618 |  CHEMBL3586033 | C34H38N4O4 | 566.702 | 7 / 2 | 5.6 | No |
| 180586 |  CHEMBL13926 | C28H32N4O4 | 488.588 | 5 / 3 | 2.4 | Yes |
| 180587 |  CHEMBL275093 | C28H32N4O4 | 488.588 | 5 / 3 | 2.4 | Yes |
| 180588 |  CHEMBL13687 | C28H32N4O4 | 488.588 | 5 / 3 | 2.4 | Yes |
| 181065 |  CHEMBL330860 | C33H42N4O3 | 542.724 | 4 / 2 | 4.6 | No |
| 182411 |  CHEMBL1080907 | C28H27N3O2 | 437.543 | 2 / 1 | 4.9 | Yes |
| 485557 |  CHEMBL3586022 | C29H28N6O3S | 540.642 | 8 / 2 | 5.2 | No |
| 185127 |  CHEMBL332414 | C32H39IN4O3 | 654.593 | 4 / 2 | 4.9 | No |
| 190671 |  CHEMBL331093 | C35H44N4O3 | 568.762 | 4 / 2 | 5.0 | No |
| 487229 |  CHEMBL3586020 | C30H29N5O3S | 539.654 | 7 / 2 | 5.8 | No |
| 202449 |  CHEMBL1082189 | C26H26N4O3 | 442.519 | 4 / 1 | 3.7 | Yes |
| 203665 |  CHEMBL1080389 | C27H24FN3O2 | 441.506 | 3 / 1 | 4.6 | Yes |
| 205408 |  CHEMBL1080162 | C26H24N4O2 | 424.504 | 3 / 1 | 3.4 | Yes |
| 205428 |  CHEMBL13933 | C24H22N6O | 410.481 | 5 / 2 | 3.1 | Yes |
| 213971 |  CHEMBL13891 | C28H34N4O3 | 474.605 | 4 / 4 | 2.3 | Yes |
| 216105 |  CHEMBL268516 | C27H27N7O2 | 481.56 | 6 / 3 | 2.9 | Yes |
| 217154 |  CHEMBL236038 | C17H23N7O2 | 357.418 | 7 / 2 | -0.6 | Yes |
| 223136 |  CHEMBL125498 | C30H38N4O3S | 534.719 | 5 / 2 | 3.9 | No |
| 229461 |  CHEMBL274599 | C28H34N4O2 | 458.606 | 3 / 3 | 3.7 | Yes |
| 234769 |  CHEMBL1088037 | C26H22F2N4O2 | 460.485 | 5 / 1 | 3.6 | Yes |
| 492082 |  CHEMBL3586028 | C27H28N4O6 | 504.543 | 9 / 2 | 3.5 | No |
| 236320 |  CHEMBL1081611 | C28H27N3O2 | 437.543 | 2 / 1 | 4.9 | Yes |
| 492649 |  CHEMBL3586029 | C30H34N4O5 | 530.625 | 8 / 2 | 4.6 | No |
| 242154 |  CHEMBL122108 | C34H42N4O3 | 554.735 | 4 / 2 | 4.6 | No |
| 242372 |  CHEMBL124831 | C34H42F2N4O4 | 608.731 | 7 / 3 | 4.2 | No |
| 242675 |  CHEMBL273682 | C33H31N7O2 | 557.658 | 6 / 3 | 4.5 | No |
| 248834 |  CHEMBL1080320 | C24H22N4O2S | 430.526 | 4 / 1 | 3.6 | Yes |
| 248860 |  CHEMBL331303 | C36H47FN4O4 | 618.794 | 6 / 3 | 4.1 | No |
| 252578 |  CHEMBL13366 | C28H32N4O3 | 472.589 | 4 / 3 | 2.7 | Yes |
| 253152 |  CHEMBL330989 | C32H39FN4O3 | 546.687 | 5 / 2 | 4.3 | No |
| 269484 |  CHEMBL275795 | C28H34N4O4 | 490.604 | 5 / 4 | 2.2 | Yes |
| 271006 |  CHEMBL268231 | C28H32N4O4 | 488.588 | 5 / 3 | 2.4 | Yes |
| 497054 |  CHEMBL3586024 | C29H29N5O5 | 527.581 | 8 / 2 | 4.5 | No |
| 554676 |  CHEMBL3358452 | C22H23F6N5O | 487.45 | 11 / 2 | 4.2 | No |
| 285112 |  CHEMBL332987 | C36H46N4O4 | 598.788 | 5 / 2 | 4.6 | No |
| 499658 |  CHEMBL3586027 | C29H25ClN4O4 | 528.993 | 7 / 2 | 5.5 | No |
| 500104 |  CHEMBL3593815 | C28H27F2N3O4 | 507.538 | 8 / 3 | 4.9 | No |
| 302955 |  CHEMBL276333 | C31H36N8O2 | 552.683 | 7 / 4 | 3.1 | No |
| 308562 |  CHEMBL262889 | C36H46N4O4 | 598.788 | 5 / 2 | 4.6 | No |
| 310084 |  L-692429 | C29H31N7O2 | 509.614 | 6 / 3 | 3.5 | No |
| 315930 |  CHEMBL13841 | C29H36N4O2 | 472.633 | 3 / 3 | 4.2 | Yes |
| 502301 |  CHEMBL3593634 | C32H34N4O5 | 554.647 | 7 / 2 | 4.5 | No |
| 333913 |  CHEMBL266836 | C28H29N7O2 | 495.587 | 6 / 3 | 3.4 | Yes |
| 340529 |  Ibutamoren | C27H36N4O5S | 528.668 | 7 / 2 | 1.3 | No |
| 340633 |  CHEMBL274340 | C28H34N4O3 | 474.605 | 4 / 3 | 3.3 | Yes |
| 346180 |  CHEMBL273215 | C27H27N7O2 | 481.56 | 6 / 3 | 2.9 | Yes |
| 506128 |  CHEMBL3586032 | C33H34N4O5 | 566.658 | 7 / 2 | 4.2 | No |
| 506176 |  CHEMBL3586026 | C28H27N5O5 | 513.554 | 8 / 2 | 4.0 | No |
| 506178 |  CHEMBL3586025 | C28H27N5O5 | 513.554 | 8 / 2 | 4.0 | No |
| 355673 |  CHEMBL369482 | C46H56N12O6 | 873.032 | 9 / 10 | 1.5 | No |
| 507050 |  CHEMBL3586023 | C30H31N5O4 | 525.609 | 7 / 2 | 4.7 | No |
| 358646 |  CHEMBL1082190 | C24H23N5O2 | 413.481 | 3 / 2 | 2.8 | Yes |
| 364550 |  CHEMBL13675 | C28H34N4O4 | 490.604 | 5 / 4 | 2.2 | Yes |
| 371976 |  CHEMBL1080938 | C26H24N4O2 | 424.504 | 3 / 1 | 3.5 | Yes |
| 382841 |  Tabimorelin | C32H40N4O3 | 528.697 | 4 / 2 | 4.2 | No |
| 383683 |  CHEMBL276272 | C32H37N7O2 | 551.695 | 6 / 3 | 5.0 | No |
| 386176 |  Ghrp-6 | C46H56N12O6 | 873.032 | 9 / 11 | 1.9 | No |
| 555237 |  growth hormone releasing hexapeptide | C46H56N12O6 | 873.032 | 9 / 11 | 1.9 | No |
| 389646 |  CHEMBL1080939 | C26H23ClN4O2 | 458.946 | 3 / 1 | 4.1 | Yes |
| 391699 |  CHEMBL277571 | C36H37N7O2 | 599.739 | 6 / 3 | 5.6 | No |
| 397147 |  CHEMBL1087908 | C26H23FN4O2 | 442.494 | 4 / 1 | 3.5 | Yes |
| 401238 |  CHEMBL274341 | C31H35N7O3 | 553.667 | 7 / 4 | 3.3 | No |
| 512488 |  CHEMBL3586019 | C79H109N19O12 | 1516.86 | 15 / 16 | 3.4 | No |
| 402944 |  CHEMBL121803 | C29H40N4O4 | 508.663 | 5 / 2 | 2.4 | No |
| 512942 |  CHEMBL3593632 | C34H36N4O5 | 580.685 | 7 / 2 | 4.5 | No |
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