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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Growth hormone secretagogue receptor type 1
Species	Rattus norvegicus (Rat)
Gene	Ghsr
Synonym	GH-releasing peptide receptor Ghrelin receptor ghrelin receptor 1a GHRP GHS-R growth hormone-releasing peptide receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	364
Amino acid sequence	MWNATPSEEPEPNVTLDLDWDASPGNDSLPDELLPLFPAPLLAGVTATCVALFVVGISGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHENGTDPRDTNECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKSSINT
UniProt	O08725
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3278
IUPHAR	246
DrugBank	N/A

Ligand

Name	CHEMBL3586025
Molecular formula	C28H27N5O5
IUPAC name	2-(1,3-benzodioxol-5-ylmethylamino)-N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-5-(1-ethylpyrazol-4-yl)pyridine-3-carboxamide
Molecular weight	513.554
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	4.0
Synonyms	BDBM50094231
Inchi Key	UZSWJTMMJHUNNT-OAQYLSRUSA-N
Inchi ID	InChI=1S/C28H27N5O5/c1-2-33-15-20(13-32-33)19-10-22(28(34)31-14-21-16-35-23-5-3-4-6-25(23)38-21)27(30-12-19)29-11-18-7-8-24-26(9-18)37-17-36-24/h3-10,12-13,15,21H,2,11,14,16-17H2,1H3,(H,29,30)(H,31,34)/t21-/m1/s1
PubChem CID	122180019
ChEMBL	CHEMBL3586025
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Efficacy	<95.0 %	PMID25981690	ChEMBL
IC50	5500.0 nM	PMID25981690	ChEMBL

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