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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	L-692,585
Molecular formula	C32H37N7O3
IUPAC name	3-[[(2R)-2-hydroxypropyl]amino]-3-methyl-N-[(3R)-2-oxo-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-4,5-dihydro-3H-1-benzazepin-3-yl]butanamide
Molecular weight	567.694
Hydrogen bond acceptor	7
Hydrogen bond donor	4
XlogP	3.8
Synonyms	145455-35-2 AKOS024457015 DTXSID40432124 MolPort-023-276-373 BRD-K70241288-001-01-1 J-008115 SCHEMBL7474014 3-[[(2R)-2-Hydroxypropyl]amino]-3-methyl-N-[(3R)-2,3,4,5-tetrahydro-2-oxo-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-1-benzazepin-3-yl]-butanamide CHEMBL13600 L-692585 B6994 FT-0771252 NCGC00159545-01 CHEBI:93230 KB-78074 ZINC3918332 CTK8E6841 L692585 BDBM50403628 HMS3268F14 RT-013487 [ Show all ]
Inchi Key	AYBCFPXLXOLPIZ-JIPXPUAJSA-N
Inchi ID	InChI=1S/C32H37N7O3/c1-21(40)19-33-32(2,3)18-29(41)34-27-17-16-24-8-4-7-11-28(24)39(31(27)42)20-22-12-14-23(15-13-22)25-9-5-6-10-26(25)30-35-37-38-36-30/h4-15,21,27,33,40H,16-20H2,1-3H3,(H,34,41)(H,35,36,37,38)/t21-,27-/m1/s1
PubChem CID	9872740
ChEMBL	CHEMBL13600
IUPHAR	N/A
BindingDB	50403628
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17288	Growth hormone secretagogue receptor type 1	O08725	Ghsr	Rattus norvegicus (Rat)	364
17289	Growth hormone-releasing hormone receptor	Q02644	Ghrhr	Rattus norvegicus (Rat)	464

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