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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Growth hormone secretagogue receptor type 1
Species	Rattus norvegicus (Rat)
Gene	Ghsr
Synonym	GH-releasing peptide receptor Ghrelin receptor ghrelin receptor 1a GHRP GHS-R growth hormone-releasing peptide receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	364
Amino acid sequence	MWNATPSEEPEPNVTLDLDWDASPGNDSLPDELLPLFPAPLLAGVTATCVALFVVGISGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHENGTDPRDTNECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKSSINT
UniProt	O08725
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3278
IUPHAR	246
DrugBank	N/A

Ligand

Name	CHEMBL441345
Molecular formula	C33H39N7O2
IUPAC name	3-methyl-3-(2-methylpropylamino)-N-[(3R)-2-oxo-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-4,5-dihydro-3H-1-benzazepin-3-yl]butanamide
Molecular weight	565.722
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	5.4
Synonyms	SCHEMBL9025440
Inchi Key	AZZPPXKHXQFGEZ-MUUNZHRXSA-N
Inchi ID	InChI=1S/C33H39N7O2/c1-22(2)20-34-33(3,4)19-30(41)35-28-18-17-25-9-5-8-12-29(25)40(32(28)42)21-23-13-15-24(16-14-23)26-10-6-7-11-27(26)31-36-38-39-37-31/h5-16,22,28,34H,17-21H2,1-4H3,(H,35,41)(H,36,37,38,39)/t28-/m1/s1
PubChem CID	18651469
ChEMBL	CHEMBL441345
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
ED50	85.0 uM	Bioorg. Med. Chem. Lett., (1994) 4:9:1117	ChEMBL

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