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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1080320
Molecular formula	C24H22N4O2S
IUPAC name	[(3S)-4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl]-[4-(1,3-thiazol-5-yl)phenyl]methanone
Molecular weight	430.526
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.6
Synonyms	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(4-(thiazol-5-yl)phenyl)methanone BDBM50312795
Inchi Key	ORTRFLDHPXAUHU-INIZCTEOSA-N
Inchi ID	InChI=1S/C24H22N4O2S/c1-16-14-27(23(29)19-5-3-18(4-6-19)22-13-25-15-31-22)10-11-28(16)24(30)20-7-2-17-8-9-26-21(17)12-20/h2-9,12-13,15-16,26H,10-11,14H2,1H3/t16-/m0/s1
PubChem CID	46880812
ChEMBL	CHEMBL1080320
IUPHAR	N/A
BindingDB	50312795
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
248834	Growth hormone secretagogue receptor type 1	O08725	Ghsr	Rattus norvegicus (Rat)	364
248835	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366

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