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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL122939
Molecular formula	C34H46N4O4S
IUPAC name	(E)-5-amino-N-[(2R)-1-[[(2R)-1-[[(2S)-2-hydroxypropyl]amino]-1-oxo-3-thiophen-2-ylpropan-2-yl]-methylamino]-1-oxo-3-(4-phenylcyclohexa-1,5-dien-1-yl)propan-2-yl]-N,5-dimethylhex-2-enamide
Molecular weight	606.826
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	3.7
Synonyms	(E)-5-Amino-5-methyl-hex-2-enoic acid [(R)-1-{[(R)-1-((S)-2-hydroxy-propylcarbamoyl)-2-thiophen-2-yl-ethyl]-methyl-carbamoyl}-2-(4-phenyl-cyclohexa-1,5-dienyl)-ethyl]-methyl-amide BDBM50066825
Inchi Key	FFZBCSXBGQSMNS-YJBWETOPSA-N
Inchi ID	InChI=1S/C34H46N4O4S/c1-24(39)23-36-32(41)29(22-28-13-10-20-43-28)38(5)33(42)30(37(4)31(40)14-9-19-34(2,3)35)21-25-15-17-27(18-16-25)26-11-7-6-8-12-26/h6-17,20,24,27,29-30,39H,18-19,21-23,35H2,1-5H3,(H,36,41)/b14-9+/t24-,27?,29+,30+/m0/s1
PubChem CID	44347919
ChEMBL	CHEMBL122939
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
77561	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366
77562	Growth hormone secretagogue receptor type 1	O08725	Ghsr	Rattus norvegicus (Rat)	364

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