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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL13926
Molecular formula	C28H32N4O4
IUPAC name	2-amino-N-[(2R)-3-(1H-indol-3-yl)-1-oxo-1-[(2S)-4-oxospiro[3H-chromene-2,3'-piperidine]-1'-yl]propan-2-yl]-2-methylpropanamide
Molecular weight	488.588
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	2.4
Synonyms	1N-[1-(1H-3-indolylmethyl)-2-oxo-2-[4-oxo-(2''S)-spiro[4H-chromene-2,3''-(hexahydropyridine)]-1-yl]-(1R)-ethyl]-2-amino-2-methylpropanamide BDBM50066103 1N-[1-(1H-3-indolylmethyl)-2-oxo-2-[4-oxo-(2''S)-spiro[3H,4H-chromene-2,3''-(hexahydropyridine)]-1-yl]-(1R)-ethyl]-2-amino-2-methylpropanamide
Inchi Key	KXMBIAQXUZZYJL-DFHRPNOPSA-N
Inchi ID	InChI=1S/C28H32N4O4/c1-27(2,29)26(35)31-22(14-18-16-30-21-10-5-3-8-19(18)21)25(34)32-13-7-12-28(17-32)15-23(33)20-9-4-6-11-24(20)36-28/h3-6,8-11,16,22,30H,7,12-15,17,29H2,1-2H3,(H,31,35)/t22-,28+/m1/s1
PubChem CID	44268939
ChEMBL	CHEMBL13926
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
180586	Growth hormone secretagogue receptor type 1	O08725	Ghsr	Rattus norvegicus (Rat)	364

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