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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1079622
Molecular formula	C26H23ClN4O2
IUPAC name	[(2S)-4-[5-(2-chlorophenyl)pyridine-2-carbonyl]-2-methylpiperazin-1-yl]-(1H-indol-6-yl)methanone
Molecular weight	458.946
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.4
Synonyms	BDBM50312790 (S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(5-(2-chlorophenyl)pyridin-2-yl)methanone
Inchi Key	AURAUMNYCSFCEU-KRWDZBQOSA-N
Inchi ID	InChI=1S/C26H23ClN4O2/c1-17-16-30(12-13-31(17)25(32)19-7-6-18-10-11-28-24(18)14-19)26(33)23-9-8-20(15-29-23)21-4-2-3-5-22(21)27/h2-11,14-15,17,28H,12-13,16H2,1H3/t17-/m0/s1
PubChem CID	46880770
ChEMBL	CHEMBL1079622
IUPHAR	N/A
BindingDB	50312790
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
14908	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366
14909	Growth hormone secretagogue receptor type 1	O08725	Ghsr	Rattus norvegicus (Rat)	364

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