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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1080389
Molecular formula	C27H24FN3O2
IUPAC name	[4-(2-fluorophenyl)phenyl]-[(3S)-4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl]methanone
Molecular weight	441.506
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.6
Synonyms	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(2''-fluorobiphenyl-4-yl)methanone BDBM50312778
Inchi Key	MESZSUFNQDICOD-SFHVURJKSA-N
Inchi ID	InChI=1S/C27H24FN3O2/c1-18-17-30(14-15-31(18)27(33)22-11-8-20-12-13-29-25(20)16-22)26(32)21-9-6-19(7-10-21)23-4-2-3-5-24(23)28/h2-13,16,18,29H,14-15,17H2,1H3/t18-/m0/s1
PubChem CID	46880628
ChEMBL	CHEMBL1080389
IUPHAR	N/A
BindingDB	50312778
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
203673	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
203668	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
203672	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
203671	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
203669	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
203665	Growth hormone secretagogue receptor type 1	O08725	Ghsr	Rattus norvegicus (Rat)	364
203666	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366
203670	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
203674	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
203667	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
203664	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590

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