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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Growth hormone secretagogue receptor type 1
Species	Rattus norvegicus (Rat)
Gene	Ghsr
Synonym	GH-releasing peptide receptor Ghrelin receptor ghrelin receptor 1a GHRP GHS-R growth hormone-releasing peptide receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	364
Amino acid sequence	MWNATPSEEPEPNVTLDLDWDASPGNDSLPDELLPLFPAPLLAGVTATCVALFVVGISGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHENGTDPRDTNECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKSSINT
UniProt	O08725
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3278
IUPHAR	246
DrugBank	N/A

Ligand

Name	CHEMBL236038
Molecular formula	C17H23N7O2
IUPAC name	2-amino-N-[(1S)-1-[1-(2-cyanoethyl)tetrazol-5-yl]-2-phenylmethoxyethyl]-2-methylpropanamide
Molecular weight	357.418
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	-0.6
Synonyms	BDBM50222148 (S)-2-amino-N-(2-(benzyloxy)-1-(1-(2-cyanoethyl)-1H-tetrazol-5-yl)ethyl)-2-methylpropanamide
Inchi Key	MYJPZNZBOVFLEU-CQSZACIVSA-N
Inchi ID	InChI=1S/C17H23N7O2/c1-17(2,19)16(25)20-14(12-26-11-13-7-4-3-5-8-13)15-21-22-23-24(15)10-6-9-18/h3-5,7-8,14H,6,10-12,19H2,1-2H3,(H,20,25)/t14-/m1/s1
PubChem CID	9950632
ChEMBL	CHEMBL236038
IUPHAR	N/A
BindingDB	50222148
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
ED50	0.0085 umol.kg-1	PMID17869100	ChEMBL

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