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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL268518
Molecular formula	C28H34N4O2
IUPAC name	2-amino-N-[(2R)-3-(1H-indol-3-yl)-1-oxo-1-spiro[1,3-dihydroindene-2,4'-piperidine]-1'-ylpropan-2-yl]-2-methylpropanamide
Molecular weight	458.606
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	3.3
Synonyms	BDBM50073030 1N-[1-(1H-3-indolylmethyl)-2-oxo-2-spiro[2,3-dihydro-1H-indene-2,4''-(hexahydropyridine)]-1-yl-(1R)-ethyl]-2-amino-2-methylpropanamide
Inchi Key	HDLPVLYONYYNIJ-XMMPIXPASA-N
Inchi ID	InChI=1S/C28H34N4O2/c1-27(2,29)26(34)31-24(15-21-18-30-23-10-6-5-9-22(21)23)25(33)32-13-11-28(12-14-32)16-19-7-3-4-8-20(19)17-28/h3-10,18,24,30H,11-17,29H2,1-2H3,(H,31,34)/t24-/m1/s1
PubChem CID	22867465
ChEMBL	CHEMBL268518
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
112073	Growth hormone secretagogue receptor type 1	O08725	Ghsr	Rattus norvegicus (Rat)	364

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