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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1080907
Molecular formula	C28H27N3O2
IUPAC name	[(3S)-4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl]-[4-(2-methylphenyl)phenyl]methanone
Molecular weight	437.543
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.9
Synonyms	(S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(2''-methylbiphenyl-4-yl)methanone BDBM50312766
Inchi Key	LADSERODBYZUAW-FQEVSTJZSA-N
Inchi ID	InChI=1S/C28H27N3O2/c1-19-5-3-4-6-25(19)21-7-10-23(11-8-21)27(32)30-15-16-31(20(2)18-30)28(33)24-12-9-22-13-14-29-26(22)17-24/h3-14,17,20,29H,15-16,18H2,1-2H3/t20-/m0/s1
PubChem CID	46880631
ChEMBL	CHEMBL1080907
IUPHAR	N/A
BindingDB	50312766
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
182414	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
182409	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
182412	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
182417	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
182415	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
182408	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366
182411	Growth hormone secretagogue receptor type 1	O08725	Ghsr	Rattus norvegicus (Rat)	364
182416	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
182410	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
182418	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
182413	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590

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