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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL328735
Molecular formula	C26H31N3O5
IUPAC name	3-[4-[(7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazol-3-yl)methyl]piperazin-1-yl]-1-phenylpropan-1-one
Molecular weight	465.55
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	2.7
Synonyms	3-[4-(7,8-Dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-3-ylmethyl)-piperazin-1-yl]-1-phenyl-propan-1-one BDBM50131358
Inchi Key	AWPNMWRTPSQMFC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H31N3O5/c1-31-23-14-19-22(15-24(23)32-2)33-17-20-25(34-27-26(19)20)16-29-12-10-28(11-13-29)9-8-21(30)18-6-4-3-5-7-18/h3-7,14-15,20,25H,8-13,16-17H2,1-2H3
PubChem CID	44325075
ChEMBL	CHEMBL328735
IUPHAR	N/A
BindingDB	50131358
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16254	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
16253	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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