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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL150161
Molecular formula	C20H21ClFNO2
IUPAC name	4-[3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl]-1-(4-fluorophenyl)butan-1-one
Molecular weight	361.841
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.9
Synonyms	SCHEMBL3122836 4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one (-)-4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one 4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one (+)-4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one (-)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one 4-[3-(4-Chloro-phenyl)-3-hydroxy-pyrrolidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one (+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one BDBM50185474 [ Show all ]
Inchi Key	BETHXCLHMRGYBW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H21ClFNO2/c21-17-7-5-16(6-8-17)20(25)11-13-23(14-20)12-1-2-19(24)15-3-9-18(22)10-4-15/h3-10,25H,1-2,11-14H2
PubChem CID	9906978
ChEMBL	CHEMBL150161
IUPHAR	N/A
BindingDB	50185474
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21898	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
21894	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
21893	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
21899	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
21896	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
21897	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
21890	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
21900	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
21889	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
21895	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
21891	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
21892	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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