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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL218675
Molecular formula	C24H30N4O
IUPAC name	[2-methyl-4-[4-(3,3,4-trimethylpiperazin-1-yl)anilino]quinolin-3-yl]methanol
Molecular weight	390.531
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.3
Synonyms	BDBM50196123 {2-methyl-4-[4-(3,3,4-trimethylpiperazin-1-yl)phenylamino]-quinolin-3-yl}methanol
Inchi Key	AANVRTGJCGRJSR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H30N4O/c1-17-21(15-29)23(20-7-5-6-8-22(20)25-17)26-18-9-11-19(12-10-18)28-14-13-27(4)24(2,3)16-28/h5-12,29H,13-16H2,1-4H3,(H,25,26)
PubChem CID	16090630
ChEMBL	CHEMBL218675
IUPHAR	N/A
BindingDB	50196123
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
370	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
369	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
368	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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