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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SK&F-106686
Molecular formula	C14H16ClNS
IUPAC name	7-chloro-2-ethyl-11-methyl-3-thia-11-azatricyclo[6.4.1.04,13]trideca-1,4(13),5,7-tetraene
Molecular weight	265.799
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	4.3
Synonyms	D07QCC 5-Chloro-1-ethyl-8-methyl-6,7,8,9-tetrahydro-2-thia-8-aza-benzo[cd]azulene SK-106686 SCHEMBL8605175 CHEMBL123448 2-Ethyl-4-methyl-7-chloro-3,4,5,6-tetrahydrothieno[4,3,2-ef][3]benzazepine BDBM50030615 [ Show all ]
Inchi Key	BAAUEDJUTZLMAN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H16ClNS/c1-3-12-10-8-16(2)7-6-9-11(15)4-5-13(17-12)14(9)10/h4-5H,3,6-8H2,1-2H3
PubChem CID	10946567
ChEMBL	CHEMBL123448
IUPHAR	N/A
BindingDB	50030615
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
18688	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
18691	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
18687	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
18686	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
18690	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
18689	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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