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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL328377
Molecular formula	C27H31N3O4
IUPAC name	3-[[4-(1H-inden-2-ylmethyl)piperazin-1-yl]methyl]-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazole
Molecular weight	461.562
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.3
Synonyms	3-[4-(1H-Inden-2-ylmethyl)-piperazin-1-ylmethyl]-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole BDBM50131356
Inchi Key	AQDOXXILINNVJB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H31N3O4/c1-31-24-13-21-23(14-25(24)32-2)33-17-22-26(34-28-27(21)22)16-30-9-7-29(8-10-30)15-18-11-19-5-3-4-6-20(19)12-18/h3-6,11,13-14,22,26H,7-10,12,15-17H2,1-2H3
PubChem CID	44324859
ChEMBL	CHEMBL328377
IUPHAR	N/A
BindingDB	50131356
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11585	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
11587	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
11586	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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