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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL425012
Molecular formula	C23H24BrF3N4O3S
IUPAC name	4-bromo-N-[[4-[(quinazolin-2-ylamino)methyl]cyclohexyl]methyl]-2-(trifluoromethoxy)benzenesulfonamide
Molecular weight	573.429
Hydrogen bond acceptor	10
Hydrogen bond donor	2
XlogP	6.1
Synonyms	BDBM50166562 4-Bromo-N-[4-(quinazolin-2-ylaminomethyl)-cyclohexylmethyl]-2-trifluoromethoxy-benzenesulfonamide
Inchi Key	BKDDSROSFZKQTN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H24BrF3N4O3S/c24-18-9-10-21(20(11-18)34-23(25,26)27)35(32,33)30-13-16-7-5-15(6-8-16)12-28-22-29-14-17-3-1-2-4-19(17)31-22/h1-4,9-11,14-16,30H,5-8,12-13H2,(H,28,29,31)
PubChem CID	44401552
ChEMBL	CHEMBL425012
IUPHAR	N/A
BindingDB	50166562
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
25678	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
25677	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
25679	Neuropeptide Y receptor type 5	Q15761	NPY5R	Homo sapiens (Human)	445

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