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Name | Neuropeptide Y receptor type 5 |
---|---|
Species | Homo sapiens (Human) |
Gene | NPY5R |
Synonym | NPYY5-R NPY5-R NPY-Y5 receptor neuropeptide Y receptor type 5 food intake receptor [ Show all ] |
Disease | Eating disorder; Obesity Eating disorder; Obesity; Diabetes Major depressive disorder Obesity |
Length | 445 |
Amino acid sequence | MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM |
UniProt | Q15761 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q15761 |
3D structure model | This predicted structure model is from GPCR-EXP Q15761. |
BioLiP | N/A |
Therapeutic Target Database | T20331 |
ChEMBL | CHEMBL4561 |
IUPHAR | 308 |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
336 | BDBM50442547 | C104H138N24O15 | 1964.4 | 20 / 19 | 6.9 | No |
868 | CHEMBL324028 | C21H23N3O3 | 365.433 | 3 / 1 | 2.1 | Yes |
1668 | CHEMBL16994 | C23H25ClN4O3S | 472.988 | 5 / 0 | 2.9 | Yes |
1793 | CHEMBL343817 | C18H19FN4 | 310.376 | 4 / 1 | 3.9 | Yes |
4018 | CHEMBL423720 | C16H18N6 | 294.362 | 5 / 1 | 1.7 | Yes |
4374 | CHEMBL523330 | C24H31N3O3S | 441.59 | 4 / 1 | 4.2 | Yes |
4904 | CHEMBL1784127 | C22H20F2N4O | 394.426 | 5 / 1 | 2.3 | Yes |
5227 | CHEMBL523945 | C17H13F2N5S | 357.383 | 7 / 1 | 2.5 | Yes |
5571 | CHEMBL522183 | C23H21F2N3 | 377.439 | 4 / 1 | 4.2 | Yes |
5728 | CHEMBL495625 | C24H22N4O4 | 430.464 | 6 / 1 | 2.8 | Yes |
6536 | CHEMBL117400 | C29H33FN4O3S | 536.666 | 7 / 2 | 4.0 | No |
6678 | CHEMBL498396 | C19H16FN3O2 | 337.354 | 5 / 1 | 3.5 | Yes |
6726 | CHEMBL7147 | C15H14N4 | 250.305 | 2 / 2 | 2.2 | Yes |
7177 | CHEMBL136974 | C19H19F3N4 | 360.384 | 6 / 1 | 4.7 | Yes |
7566 | CHEMBL269561 | C17H14FN3 | 279.318 | 3 / 1 | 3.1 | Yes |
7644 | CHEMBL494174 | C21H17F2N3 | 349.385 | 4 / 2 | 3.4 | Yes |
7914 | CHEMBL349328 | C38H49IN4O2 | 720.74 | 5 / 0 | 8.2 | No |
8570 | CHEMBL326736 | C14H11N3 | 221.263 | 2 / 1 | 2.3 | Yes |
8598 | CHEMBL331319 | C28H32F2N4O3S | 542.646 | 8 / 3 | 3.7 | No |
8639 | CHEMBL523715 | C24H25N5O3S | 463.556 | 6 / 1 | 2.2 | Yes |
8737 | CHEMBL75827 | C23H19F3N4O2S | 472.486 | 8 / 2 | 5.0 | Yes |
8871 | CID 73351118 | C184H287N53O53S2 | 4153.76 | 61 / 58 | -13.6 | No |
8983 | CHEMBL137786 | C19H18N4O | 318.38 | 4 / 2 | 3.8 | Yes |
9041 | CHEMBL133032 | C18H19N3O | 293.37 | 4 / 0 | 4.1 | Yes |
9163 | CHEMBL350379 | C28H35N3O2S | 477.667 | 5 / 2 | 4.9 | Yes |
9239 | CID 76335489 | C177H272N52O55 | 4008.43 | 62 / 60 | -15.6 | No |
9479 | BDBM50261952 | C23H25BrO4 | 445.353 | 4 / 0 | 4.1 | Yes |
10097 | CHEMBL6938 | C19H18N2O | 290.366 | 2 / 1 | 4.0 | Yes |
10606 | CHEMBL288355 | C28H33N5O3 | 487.604 | 4 / 5 | 2.9 | Yes |
11411 | CHEMBL1912066 | C19H24N4O4S3 | 468.605 | 8 / 2 | 3.1 | Yes |
11437 | CHEMBL42747 | C30H35N5O3 | 513.642 | 4 / 4 | 3.1 | No |
11938 | CHEMBL120117 | C15H10F3N3 | 289.261 | 5 / 1 | 3.2 | Yes |
12045 | CHEMBL1909718 | C16H24N4O2S2 | 368.514 | 7 / 2 | 2.8 | Yes |
12145 | Ac-Peptide YY(25-36) | C74H118N26O18 | 1659.92 | 37 / 31 | 4.7 | No |
13103 | CHEMBL61879 | C16H13F3N2O | 306.288 | 4 / 1 | 3.9 | Yes |
13872 | CHEMBL2440903 | C41H56N12O7 | 828.976 | 9 / 11 | -1.2 | No |
14162 | CID 44577739 | C27H34O4 | 422.565 | 4 / 1 | 5.8 | No |
14627 | CHEMBL360671 | C22H23BrF3N5O3S | 574.417 | 11 / 1 | 5.6 | No |
14631 | D0P9KP | C180H279N53O54 | 4049.53 | 61 / 61 | -14.9 | No |
15271 | CHEMBL304896 | C22H19N3O2 | 357.413 | 3 / 1 | 2.7 | Yes |
15355 | CHEMBL419951 | C20H23N3O2 | 337.423 | 2 / 1 | 2.9 | Yes |
16306 | CHEMBL349486 | C27H30ClN3O5S | 544.063 | 6 / 2 | 3.2 | No |
16607 | CHEMBL276322 | C23H24ClN3O4S | 473.972 | 5 / 2 | 2.6 | Yes |
19109 | CHEMBL506163 | C22H18FN5O | 387.418 | 6 / 1 | 2.6 | Yes |
19161 | CHEMBL59680 | C21H25N3O2 | 351.45 | 3 / 1 | 2.4 | Yes |
19347 | CHEMBL492375 | C25H26N4O3S | 462.568 | 5 / 1 | 2.8 | Yes |
19358 | CHEMBL118931 | C29H37N3O3S | 507.693 | 6 / 2 | 4.9 | No |
19395 | CHEMBL523819 | C22H15F2N3 | 359.38 | 4 / 1 | 3.8 | Yes |
19999 | CHEMBL164586 | C29H38N4O2S | 506.709 | 6 / 3 | 4.6 | No |
20251 | CHEMBL76512 | C18H12Cl2F3N3O | 414.209 | 5 / 1 | 5.6 | No |
20706 | CHEMBL1912074 | C13H19N3O2S3 | 345.494 | 7 / 2 | 2.8 | Yes |
21094 | CHEMBL137638 | C16H24N4 | 272.396 | 3 / 1 | 3.9 | Yes |
21345 | CHEMBL1782077 | C21H18F2N4O | 380.399 | 5 / 1 | 1.9 | Yes |
21525 | CHEMBL420541 | C18H11Cl2N3 | 340.207 | 2 / 1 | 4.9 | Yes |
22025 | CHEMBL1836319 | C18H24FN3O2S2 | 397.527 | 7 / 2 | 3.9 | Yes |
22580 | CHEMBL525543 | C20H19N3O3 | 349.39 | 5 / 1 | 3.4 | Yes |
22652 | CHEMBL312169 | C21H26FN3O3S | 419.515 | 7 / 1 | 3.1 | Yes |
23373 | CHEMBL311159 | C23H23N3O5 | 421.453 | 5 / 2 | 3.7 | Yes |
23749 | CHEMBL585711 | C22H26FN5OS2 | 459.602 | 9 / 1 | 3.8 | Yes |
23796 | CHEMBL159134 | C16H12ClN3O | 297.742 | 2 / 2 | 3.7 | Yes |
24067 | CHEMBL119726 | C22H27N3O2 | 365.477 | 2 / 1 | 3.6 | Yes |
24337 | CHEMBL495169 | C24H25N5O3S | 463.556 | 6 / 1 | 2.5 | Yes |
24895 | CHEMBL1912087 | C18H23N5O2S3 | 437.595 | 9 / 2 | 3.8 | Yes |
25679 | CHEMBL425012 | C23H24BrF3N4O3S | 573.429 | 10 / 2 | 6.1 | No |
26657 | CHEMBL16986 | C22H18ClF4N3O3S | 515.908 | 8 / 1 | 4.3 | No |
26690 | CHEMBL116210 | C22H19N3O2 | 357.413 | 3 / 1 | 3.2 | Yes |
28766 | CHEMBL1912067 | C14H17F3N4O2S2 | 394.431 | 10 / 2 | 3.3 | Yes |
29409 | CHEMBL137360 | C20H24N4 | 320.44 | 3 / 1 | 4.7 | Yes |
30527 | CHEMBL278677 | C26H23N5O2S | 469.563 | 7 / 3 | 4.7 | Yes |
30651 | CHEMBL312739 | C24H26N2O2 | 374.484 | 2 / 2 | 4.3 | Yes |
30804 | CHEMBL160722 | C22H23N3O2 | 361.445 | 3 / 2 | 4.1 | Yes |
30939 | CHEMBL526084 | C22H18ClN3O4 | 423.853 | 5 / 1 | 3.6 | Yes |
31200 | CHEMBL16965 | C26H23N5O2S | 469.563 | 7 / 3 | 4.7 | Yes |
31254 | CHEMBL165506 | C29H37N3O3S | 507.693 | 6 / 2 | 5.0 | No |
31342 | CHEMBL418546 | C23H25ClN4O4S | 488.987 | 6 / 2 | 2.0 | Yes |
31494 | CID 9930634 | C24H28O5 | 396.483 | 5 / 1 | 3.6 | Yes |
31579 | CHEMBL417225 | C20H16N4 | 312.376 | 2 / 1 | 3.8 | Yes |
31604 | CID 44439571 | C81H123N27O18 | 1763.05 | 23 / 29 | -2.0 | No |
32150 | CHEMBL304245 | C17H15F3N2O | 320.315 | 5 / 1 | 3.9 | Yes |
32967 | CHEMBL521862 | C20H15F2N3 | 335.358 | 4 / 1 | 3.0 | Yes |
33819 | BDBM50261898 | C23H25FO4 | 384.447 | 5 / 0 | 3.5 | Yes |
33838 | CHEMBL77589 | C24H26N2O2 | 374.484 | 2 / 1 | 5.6 | No |
33849 | CHEMBL292729 | C21H25N3O | 335.451 | 2 / 1 | 3.3 | Yes |
33892 | CHEMBL167860 | C27H39N3O4S | 501.686 | 7 / 3 | 3.0 | No |
35088 | CHEMBL1774211 | C57H65F3N8O7 | 1031.19 | 12 / 6 | N/A | No |
36648 | CHEMBL277551 | C24H25N5O2S | 447.557 | 7 / 3 | 4.8 | Yes |
37036 | CID 9886706 | C25H26O4 | 390.479 | 4 / 1 | 4.3 | Yes |
37424 | CHEMBL6893 | C15H13N3 | 235.29 | 2 / 1 | 2.7 | Yes |
37602 | CHEMBL418459 | C20H23N3O2 | 337.423 | 3 / 1 | 2.7 | Yes |
37703 | CHEMBL3040658 | C84H116N18O16 | 1633.96 | 18 / 17 | 2.5 | No |
38167 | CHEMBL489726 | C20H16F2N4O | 366.372 | 5 / 2 | 2.3 | Yes |
38215 | CHEMBL123410 | C22H24Cl2N2O | 403.347 | 2 / 0 | 5.4 | No |
38354 | CHEMBL294560 | C20H16N4 | 312.376 | 2 / 1 | 4.1 | Yes |
38634 | SCHEMBL14994383 | C23H26O4 | 366.457 | 4 / 1 | 3.6 | Yes |
38635 | AC1OF52R | C23H26O4 | 366.457 | 4 / 1 | 3.6 | Yes |
38640 | CHEMBL491762 | C23H26O4 | 366.457 | 4 / 1 | 3.6 | Yes |
38961 | CHEMBL117684 | C22H21N3O | 343.43 | 2 / 1 | 3.6 | Yes |
39441 | CHEMBL138172 | C20H22N4O | 334.423 | 4 / 1 | 3.5 | Yes |
40340 | CHEMBL521844 | C21H15ClF2N2 | 368.812 | 3 / 1 | 4.7 | Yes |
40438 | CHEMBL137102 | C22H30N4 | 350.51 | 3 / 2 | 6.5 | No |
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