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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL495169
Molecular formula	C24H25N5O3S
IUPAC name	1-methylsulfonyl-N-(5-phenylpyrimidin-2-yl)spiro[2H-indole-3,4'-piperidine]-1'-carboxamide
Molecular weight	463.556
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.5
Synonyms	1-(Methylsulfonyl)-N-(5-phenylpyrimidin-2-yl)-1,2-dihydro-1''H-spiro[indole-3,4''-piperidine]-1''-carboxamide BDBM50258232 SCHEMBL6216321 1-(methylsulfonyl)-N-(5-phenylpyrimidin-2-yl)spiro[indoline-3,4''-piperidine]-1''-carboxamide
Inchi Key	BICHPJZKROOPGI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H25N5O3S/c1-33(31,32)29-17-24(20-9-5-6-10-21(20)29)11-13-28(14-12-24)23(30)27-22-25-15-19(16-26-22)18-7-3-2-4-8-18/h2-10,15-16H,11-14,17H2,1H3,(H,25,26,27,30)
PubChem CID	18004895
ChEMBL	CHEMBL495169
IUPHAR	N/A
BindingDB	50258232
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
24337	Neuropeptide Y receptor type 5	Q15761	NPY5R	Homo sapiens (Human)	445

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