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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL277551
Molecular formula	C24H25N5O2S
IUPAC name	N-[(1R,2S)-2-[(4-aminoquinazolin-2-yl)amino]cyclohexyl]naphthalene-1-sulfonamide
Molecular weight	447.557
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	4.8
Synonyms	BDBM50089068 N-[2beta-(4-Amino-2-quinazolinylamino)cyclohexane-1beta-yl]naphthalene-1-sulfonamide Naphthalene-1-sulfonic acid [(1R,2S)-2-(4-amino-quinazolin-2-ylamino)-cyclohexyl]-amide
Inchi Key	BZOQBKLUIVOIDA-LEWJYISDSA-N
Inchi ID	InChI=1S/C24H25N5O2S/c25-23-18-11-3-4-12-19(18)26-24(28-23)27-20-13-5-6-14-21(20)29-32(30,31)22-15-7-9-16-8-1-2-10-17(16)22/h1-4,7-12,15,20-21,29H,5-6,13-14H2,(H3,25,26,27,28)/t20-,21+/m0/s1
PubChem CID	44271562
ChEMBL	CHEMBL277551
IUPHAR	N/A
BindingDB	50089068
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
36648	Neuropeptide Y receptor type 5	Q15761	NPY5R	Homo sapiens (Human)	445

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